Immunocompromised Children With Acute Respiratory Distress Syndrome Possess a Distinct Circulating Inflammatory Profile.

John Nguyen,Jill M Thompson, Daniel R Balcarcel,Matthew N Alder,Daniel J McKeone,E Scott Halstead,Courtney M Rowan,Robert B Lindell,Nadir Yehya

Critical care explorations（2023）

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摘要

Immunocompromised children with acute respiratory distress syndrome were characterized by elevations in pro-inflammatory and endothelial damage biomarkers. Our study provides insight into mechanisms underlying the molecular heterogeneity of this population and potentially identifies targetable pathways to mitigate their increased mortality risk.

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acute respiratory distress syndrome,immunocompromised,pediatric,stem cell transplantation

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