Cerebrospinal fluid neurofilament light chains and CXCL13 as predictive factors for clinical course of multiple sclerosis.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia(2023)

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摘要
Our data did not confirm cNfL and/or CXCL13 CSF levels were predictive factors for disease activity such as relapses and MRI activity at the time of diagnostic lumbar puncture in patients with RRMS. While cNfL CSF levels predicted higher disability only after adjustment for other known risk factors, elevated CSF CXCL13 did not predict higher disability at all.
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关键词
CXCL13,biomarkers,clinical course,multiple sclerosis,neurofilament light chain
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