Association between ten-eleven methylcytosine dioxygenase 2 genetic variation and viral load in people with HIV.

Daniel D Murray,Birgit Grund,Cameron R MacPherson,Christina Ekenberg,Adrian G Zucco,Joanne Reekie,Lourdes Dominguez-Dominguez,Preston Leung,Dahlene Fusco,Julien Gras,Jan Gerstoft,Marie Helleberg,Álvaro H Borges,Mark N Polizzotto,Jens D Lundgren

AIDS (London, England)（2023）

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摘要

Genetic variation in TET2 was associated with HIV-VL in two large antiretroviral therapy (ART)-naive clinical trial cohorts. The role of TET2 in HIV-pathogenesis warrants further investigation.

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关键词

HIV,ten-eleven methylcytosine dioxygenase 2,HIV viral load,genetics,transcriptional regulation

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