Bioequivalence studies of cetirizine tablets using the urine excretion data of healthy Ghanaian male volunteers.

Gideon Onuh,Joseph K Adu,Samuel O Bekoe,Raphael Johnson,Reimmel K Adosraku,Samuel Asare-Nkansah

Heliyon（2023）

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摘要

The locally manufactured test Cetirizine drug was found to be bioequivalent with the innovator brand and could serve as a suitable alternative to the latter. Additionally, relevant pharmacokinetic parameters for cetirizine has been established using urinary excretion data.

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关键词

Bioequivalence,Cetirizine,HPLC-UV,Pharmacopeia assessment,Urine excretion data

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