House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model.

Patricia Ramos-Ramírez,Jielu Liu,Sofia Mogren,Joshua Gregory,Malin Noreby,Anne Petrén,Ying Lei,Henric Olsson,Marianne van Hage,Jukka Kervinen,Lars Hellman,Cecilia Andersson,Gunnar Nilsson,Mikael Adner

Journal of immunology research（2023）

引用 0|浏览21

暂无评分

摘要

We here show that exposure to HDM and CDE elicits asthma-like histopathology in guinea pigs with infiltration of inflammatory cells, airway remodelling, and accumulation of primarily mucosal mast cells. The results together encourage the use of HDM and CDE allergens for the stimulation of a clinically relevant asthma model in guinea pigs.

查看译文

关键词

house dust mite,mucosal mast cells,asthma-like

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要