Characteristics and outcomes of neonates with intrapartum asphyxia managed with therapeutic hypothermia in a public tertiary hospital in South Africa.

Firdose Lambey Nakwa,Letlhogonolo Sepeng,Alison van Kwawegen,Reenu Thomas,Karabo Seake,Tshiamo Mogajane,Nandi Ntuli,Claude Ondongo-Ezhet,Samantha Kesting,Dikeledi Maureen Kgwadi,Noela Holo Bertha Kamanga,Annaleen Coetser,Jeanne Van Rensburg,Michael S. Pepper,Sithembiso C. Velaphi

BMC pediatrics（2023）

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摘要

Overall mortality in neonates with moderate-to-severe HIE was 29.0% and 17.0% in those who were cooled. Cooling was not offered to all neonates mainly because of severe clinical illness, equipment unavailability and delayed presentation, making it difficult to assess overall impact of this intervention. Prospective clinical studies need to be conducted in LMIC to further assess effect of TH in short and long-term outcomes.

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关键词

Hypoxia Ischaemic Encephalopathy (HIE),Intrapartum asphyxia,Low- and Middle- Income Countries (LMIC),Mortality,Neonates,Therapeutic hypothermia

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