Neurocognitive, Psychosocial, and Quality of Life Outcomes After Multisystem Inflammatory Syndrome in Children Admitted to the PICU.

Marieke H Otten,Corinne M P Buysse,Emmeline P Buddingh,Suzanne W J Terheggen-Lagro,Erik G J von Asmuth,Eleonore S V de Sonnaville,Naomi Ketharanathan,Heleen E Bunker-Wiersma,Lotte Haverman,Karin Hogenbirk,Matthijs de Hoog, Martien Humblet,Koen F M Joosten,Martin C J Kneyber, Geanne Krabben,Joris Lemson, Nienke M Maas,Sofie Maebe,Peter P Roeleveld,Monique van Schooneveld, Brigitte Timmers-Raaijmaakers,Dick van Waardenburg, Jennifer C Walker,Renske Wassenberg,Job B M van Woensel, Esther de Wit, Diana W Wolthuis,Annelies van Zwol,Kim J Oostrom,Hennie Knoester,Karolijn Dulfer

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies（2023）

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摘要

Children with MIS-C requiring PICU admission had normal overall intelligence 4 months after PICU discharge. Nevertheless, these children reported more emotional and behavioral problems, more PTSD, and worse QoL compared with general population norms. In a subset undergoing more extensive testing, we also identified irregularities in neurocognitive functions. Whether these impairments are caused by the viral or inflammatory response, the PICU admission, or COVID-19 restrictions remains to be investigated.

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child, follow-up, multisystem inflammatory syndrome in children, pediatric intensive care unit, psychology

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