Autophagy and senescence of rat retinal precursor cells under high glucose.

Hanhan Peng,Wentao Han,Benteng Ma,Shirui Dai,Jianfeng Long,Shu Zhou,Haoyu Li,Baihua Chen

Frontiers in endocrinology（2022）

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摘要

Our results provide evidence for the autophagy and cellular senescence mechanisms involved in retinal hyperglycemia injury, and the protective function of autophagy is limited. Further study may favour understanding the disease progression and neuroprotection of DR.

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关键词

apoptosis,autophagy,cellular senescence,computational biology,diabetic retinopathy (DR),differentially expressed genes

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