Transcriptome and single-cell analysis reveal the contribution of immunosuppressive microenvironment for promoting glioblastoma progression.

Lulu Ni,Ping Sun,Sujuan Zhang,Bin Qian,Xu Chen,Mengrui Xiong,Bing Li

Frontiers in immunology（2022）

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摘要

This research successfully found the immunosuppressive subtype and the major cell types, signal pathways, and molecules involved in the formation of the immunosuppressive subtype and will provide new clues for the improvement of GBM personalized immunotherapy in the future.

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关键词

GBM,TAM,WGCNA,immunosuppression,immunotherapy,single-cell

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