Engineering zinc oxide hybrid selenium nanoparticles for synergetic anti-tuberculosis treatment by combining Mycobacterium tuberculosis killings and host cell immunological inhibition.

Wensen Lin,Shuhao Fan,Kangsheng Liao,Yifan Huang,Yanguang Cong,Junai Zhang,Hua Jin,Yi Zhao,Yongdui Ruan,Hongmei Lu,Fen Yang,Changxian Wu,Daina Zhao,Zhendong Fu,Biying Zheng,Jun-Fa Xu,Jiang Pi

Frontiers in cellular and infection microbiology（2022）

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摘要

These ZnO-Se NPs with synergetic anti-TB efficiency by combining the Mtb killing effects and host cell immunological inhibition effects were expected to serve as novel anti-TB agents for the development of more effective anti-TB strategy.

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关键词

anti-TB agents,immunological inhibition,killing,macrophages,tuberculosis,zinc oxide-selenium nanoparticles

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