Leber's Hereditary Optic Neuropathy with Mitochondrial DNA Mutation G11778A: A Systematic Literature Review and Meta-Analysis.

Jiajia Yuan, Jiaxun Zhao,Chong Ye,Long Pang,Xin Zhang,Alvin Luk,Yangyang Du,Kai Yoon Fan,Xiaowen Zhang,Bin Li,Changzheng Chen

BioMed research international（2023）

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摘要

The G11778A mutation is a prevalent mitochondrial DNA mutation accounting for over half of LHON cases with three primary mutations. Spontaneous visual recovery is rare, and no effective treatment is currently available.

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关键词

hereditary optic neuropathy,mitochondrial dna mutation g11778a,lebers,meta-analysis

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