Proenkephalin A and bioactive adrenomedullin are useful for risk prognostication in cardiac surgery.

Aileen Hill,Deborah Bergmann,Janin Schulte,Rashad Zayat,Gernot Marx,Tim-Philipp Simon,Jana Mossanen, Anne Brücken,Christian Stoppe

Frontiers in cardiovascular medicine（2022）

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摘要

The combination of preoperative EuroSCORE II and intraoperative measurement of penKid may be more useful to predict a prolonged ICU LOS and increased mortality than EuroSCORE II alone. Bio-ADM correlates with markers of shock. More research is encouraged for early risk stratification and validation of penKid and bio-ADM as a tool involved in clinical decisions, which may enable the early initiation of organ protective strategies.

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acute kidney injury,adrenomedullin,biomarkers,cardiac surgery,critical care,proenkephalin A,prognosis,shock

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