Single-cell transcriptomic analyses provide insights into the cellular origins and drivers of brain metastasis from lung adenocarcinoma.

Zihao Wang,Yaning Wang,Mengqi Chang,Yuekun Wang,Peng Liu,Jianqiang Wu,Guige Wang,Xiaoyue Tang,Xiangyi Hui,Penghao Liu,Xiaopeng Guo,Bing Xing,Yu Wang,Zhijun Han,Wenbin Ma

Neuro-oncology（2023）

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摘要

This study clarified possible cellular origins and drivers of metastatic LUAD at single cell level, and laid a foundation for early detections of LUAD patients with a high risk of BM.

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关键词

Brain metastasis,Immune microenvironment,Lung adenocarcinoma,S100A9,scRNA-seq

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