Prediction of Biomarker Expression on Primary Pancreatic Ductal Adenocarcinoma Tissues Using Fine-Needle Biopsies: Paving the Way for a Patient-Tailored Molecular Imaging Approach.

Ruben D Houvast,Maurice van Duijvenvoorde,JiaXin Chua,Mireille Vankemmelbeke,Lindy G Durrant,Akin Inderson,Jeanin E van Hooft,J Sven D Mieog,Bert A Bonsing,Cornelis F M Sier,A Stijn L P Crobach,Alexander L Vahrmeijer,Peter J K Kuppen

Molecular diagnosis & therapy（2023）

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摘要

This study demonstrated that biomarker expression in FNB tissues is predictive for PT expression, irrespective of the application of NAT. These findings thereby provide the foundation for the clinical application of an FNB-based biomarker-screening workflow, eventually facilitating a patient-specific approach of molecular imaging tracer administration in PDAC.

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关键词

biomarker expression,adenocarcinoma,fine-needle,patient-tailored

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