Qiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling.

Guangsen Li,Yuanjie Xu, Yingxi Li,Degui Chang,Peihai Zhang,Ziyang Ma,Di'ang Chen,Yaodong You,Xiaopeng Huang,Jian Cai

Pharmaceutical biology（2023）

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摘要

QJT improved AZS mitochondrial ubiquitination and mitophagy mediated by the LKB1/AMPK/ULK1 signaling pathway. Our study provides a theoretical basis for the treatment of AZS and male infertility.

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关键词

LKB1/AMPK/ULK1,Mitophagy,mitochondria,sperm motility,traditional Chinese medicine

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