MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.

Juanmei Wang, Aimin Zhang,Furong Huang,Jun Xu,Menghua Zhao

Pediatric pulmonology（2023）

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摘要

Combined treatment could improve lung tissue injury, promote pulmonary vascular remodeling, restore lung function, and inhibit oxidative stress in BPD rats. These effects were achieved through activation of HIF-1α.

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关键词

HIF-1α,MSC-EXO,bronchopulmonary dysplasia,tempol

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