Tobacco Cessation Motivations, Preferences, and Barriers Among Rural Smokers: Implications for Optimizing Referrals in Clinical Practice

•Nicotine replacement medications and reward-based lottery approaches are preferred cessation methods.•Cessation barriers among rural smokers include coping with stress, scheduling counseling, and finding coaches.•Nicotine replacement medications and reward-based approaches can be used to enhance smoking cessation among rural smokers.