APOE Allele Frequency in Southern Greece: Exploring the Role of Geographical Gradient in the Greek Population.

Vasiliki Papastefanopoulou,Evangelia Stanitsa,Christos Koros, Aimilios Simoudis,Chryseis Florou-Hatziyiannidou,Ion Beratis,Roubina Antonelou,Nikolaos Andronas,Panagiota Voskou,Efthalia Angelopoulou,John D Papatriantafyllou,Leonidas Stefanis,Christos Kroupis,Sokratis G Papageorgiou

Geriatrics (Basel, Switzerland)（2022）

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摘要

this study examines the isoforms and is the first to report a higher frequency in MCI compared with healthy controls in southern Greece. Importantly, we report the occurrence of the allele, related to ADD, as amongst the lowest globally reported, even within the nation, thus enhancing the theory of ethnicity and latitude contribution.

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关键词

Alzheimer’s disease,Apolipoprotein E,Greek population,mild cognitive impairment

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