Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial.

Viktor Rotbain Curovic,Niels Jongs,Marjolein Y A M Kroonen,Emilie H Zobel,Tine W Hansen,Taha Sen,Gozewijn D Laverman,Adriaan Kooy,Frederik Persson,Peter Rossing,Hiddo J L Heerspink

Diabetes care（2023）

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摘要

We demonstrated a large and reproducible variation in participants' responses to different UACR-lowering drug classes. These data support systematic rotation through different drug classes to overcome therapy resistance to RAS inhibition.

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关键词

diabetes,different drug classes,crossover rotation,albuminuria-lowering

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