Control of occult hepatitis B virus infection

Lalana Garcés Marta,Ortiz Pastor Oihana,Solé Enrech Gemma, Guerra-Ruiz Armando R.,Casals Mercadal Gregori,Almería Lafuente Alejandro, Ballesteros Vizoso María Antonieta,Medina Pablo Gabriel,Salgüero Fernández Sergio,Zamora Trillo Angielys,Aured de la Serna Isabel,Hurtado Juan Carlos,Pérez-Del-Pulgar Sofía,Forns Xavier,Morales Ruiz Manuel

Advances in Laboratory Medicine（2022）

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摘要

The diagnosis of hepatitis B virus (HBV) infection requires HBV DNA testing and serologic testing for detection of the surface antigen (HBsAg) and the hepatitis B core antibody (anti-HBc). There is a population of patients with occult HBV infection (OBI), which is not detected by HBsAg or HBV DNA quantification in blood, despite the presence of active replication in the liver.

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关键词

covalently closed circular dna (cccdna),occult hbv infection (obi),ultra-sensitive hepatitis b virus surface antigen (ultra-sensitive hbsag)

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