5S rRNA pseudogene transcripts are associated with interferon production and inflammatory responses in alcohol-associated hepatitis.

Jianguo Wu,Adam Kim,Xiaoqin Wu,Semanti Ray,Daniela S Allende,Nicole Welch,Annette Bellar,Jaividhya Dasarathy,Srinivasan Dasarathy,Laura E Nagy

Hepatology (Baltimore, Md.)（2023）

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摘要

Increased expression and binding availability of RNA5SP transcripts was associated with hepatic IFN production and inflammation in sAH. These data identify RNA5SP transcripts as a potential target to mitigate inflammation and hepatocellular injury in AH.

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关键词

5s rrna pseudogene transcripts,inflammatory responses,interferon production,alcohol-associated

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