Reply to Josef Finsterer about the article ‘What does epileptic nystagmus show us in cases presenting acute neurological symptoms?’

Thank you for the opportunity to respond to the letter from Dr. Josef Finsterer and to discuss his questions about our article. We read his letter with great interest and we would like to provide the following clarifications about our article. Epileptic nystagmus in MELAS and non-mitochondrial disordersSeizure - European Journal of EpilepsyVol. 104PreviewWe eagerly read the article by Aykac et al. about 20 patients with horizontal epileptic nystagmus [1]. One of these patients was reported as having mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome [1]. It was found that the ictal discharge pattern was rhythmic fast activity with a mean frequency of 15 Hz, that ictal discharges originated from the parieto-occipital, temporo-occipital, parieto-occipito-temporal, temporal, occipital, or centro-parietal areas, that the fast phase of the nystagmus was beating away from the side of ictal discharges, and that the origin of the ictal discharges was compatible with the lesion localization on cerebral magnetic resonance imaging (MRI) [1]. Full-Text PDF