Mitochondrial dysfunction in a rat model and the related risk of metabolic disorders.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan(2023)
摘要
KYD rats exhibited reduced mito-chondrial function in the brown fat, but were partially compensated by skeletal muscle, associated with the phenotype of warm preference and metabolic disorder, which was further exacerbated by additional HFD consumption. Future studies can focus on treatment targetting mitochondria function to reverse this phenotype.
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关键词
DNA, mitochondrial,adenosine triphosphate,kidney deficiency,peroxisome proliferator-activated receptor gamma coactivator 1-alpha,thermogenesis
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