Impact of carbapenem antibiotics on mycophenolate mofetil in hematopoietic stem cell transplant patients with interruption of the enterohepatic recycling: a retrospective study.

Ji-Xin Tian,Wen-Juan Miao,Hai-Hong Yan, Xiao-Dan Wang,Ying-Xi Liao, Shan Li,Er-Lie Jiang,Ping Zhang

Annals of translational medicine（2023）

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摘要

CBP decreased the MPA C in Chinese HSCT patients even when MMF is used in combination with cyclosporine and rifaximin. If antibiotics must be used, and CBP in particular, therapeutic drug monitoring should be performed to ensure adequate exposure.

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关键词

Antibiotics,hematopoietic stem cell transplantation (HSCT),mycophenolate mofetil (MMF),mycophenolic acid (MPA)

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