Comparison of PSMA-based 18 F-DCFPyL PET/CT and pelvic multiparametric MRI for lesion detection in the pelvis in patients with prostate cancer.

Our study demonstrated that PSMA-based F-DCFPyL PET/CT and pelvic mpMRI have a good concordance rate in the detection of primary or recurrence prostate disease and can have complementary roles in the clinical assessment of the prostate bed lesions. However, there are key differences in their performance, with the notably superior performance of PSMA-based F-DCFPyL PET/CT in the detection of small metastatic nodal disease and bone metastases.