Genistein Inhibits Clostridioides difficile Infection via Estrogen Receptors and Lysine-Deficient Protein Kinase 1.

Ying Xie,Lindsey Fontenot, Andrea Chupina Estrada, Becca Nelson, Ashlen Bullock,Kym F Faull,Hanping Feng,Mingjun Sun,Hon Wai Koon

The Journal of infectious diseases（2023）

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摘要

Genistein reduces CDI disease activity by inhibiting proinflammatory cytokine expression and apoptosis via the estrogen receptor/G-protein estrogen receptor/WNK1 pathways.

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关键词

apoptosis,cytokine,gender,hormone,isoflavone

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