Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behaviours.

Annals of the rheumatic diseases（2023）

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摘要

CHRFAM7A is an aggravating factor for OA-associated inflammation and tissue damage and a novel genetic risk factor and therapeutic target for pain.

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关键词

chondrocytes,inflammation,osteoarthritis

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