Dupilumab monotherapy suppresses recalcitrant pemphigus vulgaris

JAAD Case Reports(2023)

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摘要
Pemphigus Vulgaris (PV) is a subgroup of IgG-mediated autoimmune blistering diseases targeting desmosomal adhesion proteins, desmoglein (Dsg) 1 and Dsg 3.1 Systemic corticosteroids are the current first-line treatment. Other treatments aimed at disease control include immunosuppressive and immunomodulatory agents, such as azathioprine, mycophenolate mofetil, cyclosporine, intravenous immunoglobulin, dapsone, and rituximab.
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关键词
case report,drug response,dupilumab,general dermatology,medical dermatology,oncology,pemphigus,vesiculobullous
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