Platelet-Mimicking Nanosponges for Functional Reversal of Antiplatelet Agents.

Junchao Xu,Na Yan,Chunling Wang, Chao Gao,Xuexiang Han,Chengzhi Yang,Jiaqi Xu,Kun Wang,Michael J Mitchell,Yinlong Zhang,Guangjun Nie

Circulation research（2023）

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摘要

This study demonstrated the safety and effectiveness of platelet-mimicking nanosponges in ameliorating the bleeding risk of different APAs, which offers a promising strategy for the management of bleeding complications induced by antiplatelet therapy.

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关键词

antiplatelet agents,antithrombotic reversal agents,bio-inspired engineering,hemorrhage,platelet transfusion,theranostic nanomedicine

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