Clinical characterization of hcc/ccc mixed cancers in a population-based cohort

Diagnosis of hepatocelluar-carcinoma favors imaging modalities and biopsy is performed in only a minority of patients. Tumors displaying partially characteristics of cholangiocarcinoma (CCA) and being characterized as mixed HCC/CCA tumors may not be identified. However, these tumors may benefit from alternative treatment strategies. The aim of our study was to characterize the clinical course of HCC/CCA cancers to evaluate the need of distinct treatment options.