PET/CT Evaluation of the Effect of Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of T-Cell Lymphoblastic Lymphoma

CONTRAST MEDIA & MOLECULAR IMAGING(2022)

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摘要
The aim of this study was to investigate the clinical value of positron emission tomography/computerized tomography scanning (PET/CT) in the evaluation of the effect of allogeneic hematopoietic stem cell transplantation in the treatment of T lymphoblastic lymphoma. 12 relevant research articles were collected through layer-by-layer screening in large databases such as Pubmed, Baidu Scholar, and China How Net, and analyzed and summarized using indicators such as progression-free survival (PFS), overall survival (OS), hazard ratio (HR), maximum standardized uptake value (SUV max), total metabolic tumor volume (TMTV), total lesion glycolysis (TLG), elevated lactate dehydrogenase (LDH), and beta 2-microglobulin (beta 2-MG). The results showed that before treatment, F-18-FDG PET/CT baseline diagnosis could accurately stage the patients; during treatment, F-18-FDG PET/CT detection could provide effective treatment information; and after treatment, complications were found during F-18-FDG PET/CT detection. In summary, F-18-FDG PET/CT can monitor and evaluate treatment prognosis at baseline, middle, and late stages, and F-18-FDG PET/CT has become an indispensable and important examination technique in clinical work.
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