Light chain cardiac amyloidosis in a nonagenarian

JOURNAL OF GERIATRIC CARDIOLOGY(2022)

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摘要
Cardiac amyloidosis is an infiltrative and restrictive cardiomyopathy caused by the extracellular deposition of amyloid fibrils within the heart as systemic amyloidosis, leading to heart failure, reduced quality of life, and death.[1]There are two major amyloid fibril proteins that affect the heart: amyloid immunoglobulin light chain (AL) and amyloid transthyretin (ATTR). The latter is further subdivided into wild-type ATTR and variant types based on the presence of a mutation in the transthyretin gene.
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