Automated and rapid KRAS mutation testing in non-small cell lung cancer

Detecting KRAS mutations in tumor samples can be challenging in low-middle-income countries due to limited access to molecular biology laboratories. The Idylla TM KRAS mutation test (IKMT) is an IVD, automated, and rapid qPCR assay to detect KRAS mutations, validated in colorectal cancer. We studied the concordance of the IKMT in KRAS mutation detection, compared with NGS, and performed a prospective KRAS mutation test feasibility study in samples from patients with NSCLC.