Assessing the variability and the role of inflammatory cytokines and monocyte chemoattractant protein-1 (MCP-1) in predicting stroke among hypertensives: A case-control study

Samuel Asamoah Sakyi, Afia Serwaa Opoku,Benjamin Amoani,Bright Oppong Afranie,Alexander Kwarteng, Richard Dadzie Ephriam,Stephen Opoku,Ebenezer Senu, Ebenezer Aidoo,Fred Stephen Sarfo

Dialogues in Health（2022）

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摘要

•Atherosclerosis is a complex lipid-driven disease which involves many cell types and inflammatory mediators.•Mediators’ markers that could predict the progression of hypertension to stroke are of research importance•High levels of IL-10 and MCP-1 could serve as a good predictor of stroke among hypertensives.•MCP-1 may prove useful as a therapeutic target in the prevention of atherosclerotic lesion development•Combined bioscore of MCP-1 and IL-10 could serve as a good predictor of stroke among hypertensives

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关键词

Inflammation,Stroke,Hypertension,Cytokines,Interleukin-10,monocyte chemoattractant protein-1 (MCP-1)

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