SYSTEMS-2: A randomised phase II study of radiotherapy dose escalation for pain control in malignant pleural mesothelioma

M. Ashton, N. O'Rourke, N. Macleod,B. Laird,J. Stobo,C. Kelly,L. Alexander,K. Franks, K. Moore, S. Currie, R. Valentine, A.J. Chalmers

Clinical and Translational Radiation Oncology（2018）

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摘要

SYSTEMS-2 is a randomised study of radiotherapy dose escalation for pain control in 112 patients with malignant pleural mesothelioma (MPM). Standard palliative (20 Gy/5#) or dose escalated treatment (36 Gy/6#) will be delivered using advanced radiotherapy techniques and pain responses will be compared at week 5. Data will guide optimal palliative radiotherapy in MPM.

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