Body composition and anthropometric indices in pre- and postmenopausal women with breast cancer

Introduction: Breast cancer is the second most common cancer worldwide and the most common cancer among women and notably the fourth leading cause of death worldwide. Overweight and obesity are two main risk factors which have been proven the creation of breast cancer after menopause. Therefore, this study aimed to investigate the relationship between anthropometric and body composition in pre-menopausal and post-menopausal breast cancer risk. Materials and Methods: In this case-control study, 88 patients with breast cancer (n = 48 pre-menopausal and post-menopausal 41) and 86 controls (45 premenopausal and 41 postmenopausal) who were matched by age, studied respectively. The cases, women who were admitted to Shohada Hospital recently diagnosed with breast cancer and had not chemotherapy or radiation therapy. The controls of women who were admitted to the same hospital had no history of any type of cancer or hormonal disease. The subjects were studied anthropometric indices and body composition was also measured by tanita Body Composition analyzer. For analysis the findings, chi-square and logistic regression was used. Results: In the study of case and control groups separately menopausal status, in pre-menopausal population, overweight women (BMI=24/91-29/9kg/m2) had lower odds ratio of developing breast cancer (OR=0/23 CI=0/84-0/06). In postmenopausal population with waist-to-hip ratio (0/80-0/84), WHR was significantly associated with breast cancer risk (OR=0/09 CI=0/60-0/02). Conclusion: In this study, premenopausal overweight women had lower odds ratio of developing breast cancer. High WHR was associated with breast cancer risk in postmenopausal women.