Outcomes of extracorporeal membrane oxygenation in immunosuppressed vs. Immunocompetent patients

•We compared the outcomes of immunocompetent patients, chronically immunosuppressed patients, and acutely immunosuppressed patients who were placed on ECMO at our institution.•There was no significant difference in ECMO, 30-day, 90-day, or one-year survival between immunocompetent patients, chronically immunosuppressed patients, and acutely immunosuppressed patients, suggesting that select immunosuppressed patients may be eligible for ECMO therapy.•Acutely immunosuppressed patients were at higher risk of developing new infections on ECMO, suggesting that infection control on ECMO is important in acutely immunosuppressed patients.