Expression levels of MIF, NLRP1 and FOXP3 genes along with biomarker levels in patients with active form of non-segmental generalized vitiligo: A study in South Indian population

Alokananda Chakraborty, Seelamneni Thulasamma, Shravan Kumar Ghali,Priyanka Pallapolu,Kuna Lahari,Towseef Amin Rafeeqi,Gulam Mohammed Husain, Farhath Jabeen,Ghazala Javed, Mohammed Abdul Waheed,Munawwar Husain Kazmi

Songklanakarin Journal of Science and Technology (SJST)（2022）

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摘要

Vitiligo, the most widespread hypopigmentary syndrome, is considered to be a multifactorial disease in which the active melanocytes are lost. Vitiligo has been studied in a variety of ways, and several genes have been implicated. In this study we focused on investigating biomarker levels of TNF-α, MDA and TAS by using ELISA, and along with that mRNA expression levels of MIF, NLRP1 and FoxP3 genes were quantified with qRT-PCR. In expression studies, Non-segmental Generalized Vitiligo (NSV) subjects had a substantial (P

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关键词

vitiligo,mif,nlrp1,foxp3,tnf-α,mda,tas

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