Inhibition of SARS-CoV2 viral infection with natural antiviral plants constituents: An in-silico approach.

Kuntal Das,Paramita Das,Mansour Almuqbil,Syed Mohammed Basheeruddin Asdaq, K Nikhil,K Preethi, A Angelinkiruba,Nasser Fawzan Alomar,Rawabi M Al Harbi,Walaa A Al Abdullah, Sami M Alshehri,Yahya A Laghabi, Ahmed R Alsaegh,Yahya Mohzari,Sultan Alshehri,Basheerahmed Abdulaziz Mannasaheb,Syed Imam Rabbani

Journal of King Saud University. Science（2023）

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摘要

The phytoconstituents were found to hinder the early stages of infection, such as absorption and penetration, while ivermectin prevented the passage of genetic material from the cytoplasm to the nucleus. Additional research involving living tissues and clinical trials are suggested to corroborate the computational findings.

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关键词

Antioxidant,COVID-19,Molecular docking,Natural product,Pharmacokinetics,Toxicity

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