High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes.

G H Dørflinger, P H Høyem,E Laugesen,J A Østergaard,K L Funck, R Steffensen,P L Poulsen, T K Hansen,M Bjerre

Frontiers in immunology（2022）

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摘要

Contrary to T1D, T2D is not associated with increased MBL serum level for a given MBL genotype or with diabetes duration. Serum MBL was inversely correlated with body fat percentage, and T2D patients with the high MBL expression genotype presented with deterioration of renal function.

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关键词

MBL genotypes,T2D,albuminuria,diabetes duration,mannan-binding lectin

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