Identification of abnormally methylated differentially expressed genes in chronic periodontitis by integrated bioinformatics analysis.

Xiufen Tian,Juan Zheng,Yuanyuan Luo,Chengshi Wei,Jing Ma,Dawei Wang,Keyi Li

Technology and health care : official journal of the European Society for Engineering and Medicine（2022）

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摘要

Based on the comprehensive bioinformatics analysis, six hub genes (IL1B, KDR, MMP9, CDSN DSG1, and KRT2) were associated with chronic periodontitis. Our findings provide novel insights into the mechanisms underlying epigenetic changes in chronic periodontitis.

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关键词

Periodontitis,bioinformatic analysis,hub genes,methylation,protein-protein interaction,transcription

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