TDP-43 Pathology in the Setting of Intermediate and High Alzheimer's Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups.

Emily Z Huie,Anthony Escudero,Naomi Saito,Danielle Harvey,My-Le Nguyen,Katherine L Lucot,Jayne LaGrande,Dan Mungas,Charles DeCarli,Melissa Lamar,Julie A Schneider,Alifiya Kapasi,Robert A Rissman,Andrew F Teich,Brittany N Dugger

Journal of Alzheimer's disease : JAD（2023）

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摘要

While this is a preliminary evaluation, it highlights the need for diverse cohorts and on TDP-43 pathology research across ethnoracial groups. This is the first study to our knowledge having a focus on the neuroanatomical distribution of TDP-43 deposits in Hispanic/Latino decedents with AD.

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African American,Alzheimer’s disease,Asian,Hispanic,Latino,brain,cohort studies,minoritized groups,neuropathology

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