Morphological evaluation of HAp nanostructures and its shape-dependent protein adsorption study

The main purpose of contemporary biomaterial research is to use cost-efficient bioactive and biocompatible materials to replace damaged bone. In the current study, cuttlefish (Sepiaofficinalis) bone powder was used as a precursor in the production of hydroxyapatite nanostructures (HAp NS) utilizing the silicon oil bath-mediated precipitation technique. The reaction was performed in various time periods such as 6, 12, 24, 48 and 60 h (h) at 90 °C to prepare HAp nanostructures with diverse morphologies. XRD, FTIR, and FESEM were used to characterize the produced HAp NS, and its capacity for protein adsorption was also assessed. Furthermore, it was evidenced that modulation of cellular activities and tissue functions in human bones is mostly controlled by the shape and crystallographic properties of hydroxyapatite (HAp) nanostructures.