Fish Oil - Omega-3 Exerts Protective Effect in Oxidative Stress and Liver Dysfunctions Resulting from Experimental Sepsis

Mary J. Soares Gonçalves Velasque,Gisele Branchini,Anderson V. Catarina,Lais Bettoni,Renata S. Fernandes, Arthur Ferreira Da Silva,Gilson P. Dorneles,Igor Martins da Silva,Maeli A. Santos, Juliana Sumienski,Alessandra Peres, Adriana V. Roehe, Maria B. da Fonte Kohek,Marilene Porawski,Fernanda B. Nunes

Journal of Clinical and Experimental Hepatology（2023）

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摘要

In sepsis, one of the main affected organs is the liver, initially through inflammation to oxidative stress and cell death.Omega-3 fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), they're part of the main families of polyunsaturated fatty acids. Based on the results of the study, we can suggest that ω3 treatment has a protector effect in liver injuries, oxidative stress, and antioxidant enzymes elevation resulting during experimental sepsis.Image 1

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sepsis,omega-3,Liver injury,oxidative stress,antioxidant,inflammation

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