Safety and Immunogenicity of Influenza A/H5N8 Virus Vaccine in Healthy Adults: Durability and Cross-reactivity of Antibody Responses.

Kathleen M Neuzil,Evan J Anderson,Robert W Frenck,Sharon E Frey,Emmanuel B Walter,Richard Rupp,Elizabeth T Rotrosen,Nadine G Rouphael,Rebecca C Brady,Irene Graham,Kenneth E Schmader,Laura Porterfield,Justin R Ortiz,Geeta K Swamy,Hana M El Sahly,Trushar Jeevan, Ranjan Sitaula,Ashley Wegel,Richard J Webby,Christopher Bryant

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Two doses of influenza A/H5N8 vaccine were well-tolerated. Immunogenicity improved with receipt of two doses of adjuvanted vaccine and higher antigen content. (Funded by the National Institute of Allergy and Infectious Diseases.

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adjuvants,avian influenza,immunogenicity,influenza vaccine

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