Lessons from resistance analysis in clinical trials of IV zanamivir

Phillip J Yates,Nalini Mehta,Helen A Watson,Amanda F Peppercorn

Virus Research（2023）

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摘要

•Resistance analysis of influenza viruses isolated from a phase III clinical trial of IV zanamivir.•Identification of minority species harbouring resistance associated amino acid substitutions.•Comparison of population sequencing and next generation sequencing.

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关键词

Influenza,Intravenous zanamivir,Oseltamivir

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