CFracture, an alternative to QFracture that accounts for mortality to better predict fragility fracture risk

One in two women and one in five men over the age of 50 years are estimated to sustain one or more fragility fractures—a low-trauma fracture sustained from a fall, slip, or trip from standing height or less—in their lifetime.1 In the UK, this estimate translates to approximately 549 000 fragility fracture per year,2 costing the National Health Service more than £4·7 billion.3 Similarly, across Europe, an estimated 4·3 million fragility fractures per year result in health-care costs in excess of €56·9 billion annually.