Chondroblastoma: clinicopathological analyses of 307 cases from a single institution in China and the diagnostic value of the H3F3 K36M mutant antibody.

Qianqian Zhao,Juan Tang,Yanli Luo,Jin Huang,Dingjun Hu,Jinyu Zhu,Ting Jiang,Huizhen Zhang,Zhiyan Liu

Journal of clinical pathology（2023）

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摘要

CB usually involves the long tubular bones in younger age group. H3F3 K36M can identify K36M mutation with 100% specificity and 100% sensitivity in non-decalcified and EDTA decalcified samples, more than 80% sensitivity in HCl decalcified samples. Virtually, all CBs harbour an H3K36M mutation.

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关键词

Bone Neoplasms,IMMUNOHISTOCHEMISTRY,Morphological and Microscopic Findings,Pathology, Surgical

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