All Staphylococcus aureus bacteraemia-inducing strains can cause infective endocarditis: Results of GWAS and experimental animal studies

Journal of Infection（2023）

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摘要

•Staphylococcus aureus bacteraemia (SAB) can lead to infective endocarditis (IE).•Specific traits of IE-causing strains versus SAB-only are questioned.•GWAS from IE and SAB-only strains does not discriminate the 2 groups.•In murine and rabbit IE models, IE and SAB-only strains behave in the same way.

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关键词

Infective endocarditis,Bacteraemia,Genome-wide association study,Experimental animal model,Staphylococcus aureus

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