Predictors of patient-reported fatigue symptom severity in a nationwide multiple sclerosis cohort

Simon Englund,Marie Kierkegaard,Joachim Burman,Katharina Fink,Anna Fogdell-Hahn,Martin Gunnarsson,Jan Hillert,Annette Langer-Gould,Jan Lycke, Petra Nilsson,Jonatan Salzer,Anders Svenningsson,Johan Mellergård,Tomas Olsson,Elisa Longinetti,Thomas Frisell,Fredrik Piehl

Multiple Sclerosis and Related Disorders（2023）

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摘要

•We addressed self-reported fatigue and its association with a number of covariates.•Higher disability stood out as the best predictor of fatigue among MS-characteristics.•A clinically meaningful association with cognitive processing speed was evident.•Associations to most other disease characteristics were small.•Self-reported fatigue was highly correlated with low quality of life rating.

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关键词

Multiple sclerosis,Fatigue,Cohort studies,Quality of life,Health-related quality of life,Comorbidity

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